CYP24A1 Is an Independent Prognostic Marker of Survival in Patients with Lung Adenocarcinoma Running Title: CYP24A1 Prognostic Marker in Lung Adenocarcinoma
نویسندگان
چکیده
Authors’ Affiliations: Section of Thoracic Surgery, Department of Surgery, Division of Medical Oncology, Department of Medicine, Biostatistics Unit, Comprehensive Cancer Center, Department of Pharmacology, School of Medicine, Division of Pulmonary Medicine, Department of Medicine, Department of Pathology, University of Michigan, Ann Arbor, MI 48109 and the Veterans Administration Medical Center, Ann Arbor, MI 48109
منابع مشابه
CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma.
PURPOSE The active form of vitamin D, 1α,25-dihydroxyvitamin D(3) (1,25-D(3)), exerts antiproliferative effects in cancers, including lung adenocarcinoma (AC). CYP24A1 is overexpressed in many cancers and encodes the enzyme that catabolizes 1,25-D(3). The purpose of our study was to assess CYP24A1 as a prognostic marker and to study its relevance to antiproliferative activity of 1,25-D(3) in lu...
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تاریخ انتشار 2010